Here is the safe condition.
The bottle is upright. The lid is screwed on tightly. Emphasis on that last word. Otherwise, you're the one who's screwed.
Here's the dangerous position.
The lid is hanging loose. One little gravity surge, and you're all wet.
There will be further instruction later after you absorb these first two rules.
text tapped from a virtual keyboard. You found misspellings? Imagine that. Get over it.